CARDIAC MUSCARINIC RECEPTORS IN CONOTRUNCAL ABNORMALITIES
نویسندگان
چکیده
منابع مشابه
P136: Role of Muscarinic Receptors in Schizophrenia
Schizophrenia is a severe psychiatric illness with a lifetime prevalence of ˜1% that imposes a huge toll on patients, their families and public health services worldwide. Delusions, hallucinations, disorganized speech, grossly disorganized or catatonic behavior and negative symptoms constitute the core symptoms of schizophrenia. Although the neurotransmitter dopamine plays a prominent role in t...
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The M 1 muscarinic receptor antagonist pirenzepine in low doses decreases resting heart rate; this effect declines with age (Poller, U., G. Nedelka, J. Radke, K. Pönicke, and O.-E. Brodde. 1997. J. Am. Coll. Cardiol. 29:187–193). To study possible mechanisms underlying this effect, we assessed ( a ) in six young (26 yr old) and six older volunteers (61 yr old), pirenzepine effects (0.32 and 0.6...
متن کاملp136: role of muscarinic receptors in schizophrenia
schizophrenia is a severe psychiatric illness with a lifetime prevalence of ˜1% that imposes a huge toll on patients, their families and public health services worldwide. delusions, hallucinations, disorganized speech, grossly disorganized or catatonic behavior and negative symptoms constitute the core symptoms of schizophrenia. although the neurotransmitter dopamine plays a prominent role in t...
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The characterization of pharmacological receptors in subcellular preparations has, to date, relied mainly on observations of the binding properties of radioactively labelled ligands. Minimal criteria for receptor-specific binding are that a component of binding should saturate with increasing concentrations of the ligand and that only drugs with the appropriate pharmacological specificity, and ...
متن کاملRisk factors for conotruncal cardiac defects in Atlanta.
Because the causes of conotruncal cardiac defects are poorly understood, a case-control study was conducted to investigate maternal risk factors for conotruncal cardiac defects. Eligible cases included all infants who were born from 1976 through 1980 to residents of the five county metropolitan Atlanta area and diagnosed with truncus arteriosus, transposition of the great arteries or tetralogy ...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1987
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198704010-00128